“Replace cosmetic procedures and toxins with clean active ingredients.” 

MACRENE Actives, a luxury skincare line developed by Dr. Macrene Alexiades, a world-renowned dermatologist and scientist, leverages the best of nature and science. Their unique formulas combine potent, plant-based actives, sourced from both land and sea, to create effective one-step solutions that promote total skin health and a youthful glow. Dr. Alexiades' commitment extends beyond the lab, with many of the brand's 50+ organic ingredients cultivated on her own farm. Designed to combat environmental damage, fortify the skin's barrier, and provide antioxidant protection, MACRENE Actives offers a powerful alternative to invasive procedures.